Health Tip: Identifying Vascular Dementia

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(HealthDay News) — Vascular dementia may be the second most typical type of dementia, behind Alzheimer’s.

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Vascular dementia typically occurs following a stroke, however it can happen for some other reasons.

The U.S. National Institute on Aging identifies three common forms:

  • Multi-infarct dementia — This happens after a number of small strokes that damage cognitive abilities.
  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) — This inherited form produces a thickening from the walls of small- and medium-sized bloodstream vessels, eventually stemming the flow of bloodstream towards the brain.
  • Subcortical vascular dementia, also calledBinswanger’s disease — This rare form involves extensive harm to the little bloodstream vessels and nerve fibers that comprise white-colored matter, negligence the mind believed crucial for relaying messages between regions.

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Is Dementia Declining Among Older Americans?

News Picture: Is Dementia Declining Among Older Americans?By Steven Reinberg
HealthDay Reporter

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TUESDAY, Sept. 5, 2017 (HealthDay News) — Here’s what’s promising for America’s seniors: The rates of Alzheimer’s along with other types of dementia have dropped considerably during the last decade approximately, new research shows.

Case study of nearly 1,400 women and men 70 and older discovered that the amount of dementia cases dropped from 73 among individuals born before 1920 to simply 3 among individuals born after 1929.

The reason why for that decline aren’t obvious, researchers stated. Only one factor sticks out: The rates of stroke and cardiac arrest decreased across generations. The speed of diabetes, however, has elevated.

“It might be that we’re seeing the advantages of many years of success in coronary disease prevention,” stated lead investigator Carol Derby, an investigation professor in the Albert Einstein College of drugs in New You are able to City.

That does not seem to account for all those reduction in dementia rates, however.

Even though the rate of dementia has declined, the particular number of individuals with dementia is anticipated to improve dramatically because the population bubble brought on by seniors ages, Derby stated.

“If the changes from the rate from the start of dementia will offset that population shift remains seen,” she stated.

All over the world, greater than 47 million people are afflicted by dementia, and seven million new cases develop every year, based on the researchers.

The amount of installments of dementia is forecasted to double every twenty years, and also to achieve 115 million by 2050.

The amount of people struggling with Alzheimer’s, the most typical reason for dementia, is anticipated to climb to 106 million by 2050, the investigators stated.

“As the rates might be going lower, the issue is not even close to disappearing,Inch stated James Hendrix, director of worldwide science initiatives in the Alzheimer’s Association.

Dementia, an impairment of brain functions marked largely by memory problems and personality changes, continues to be probably the most costly chronic conditions, with a big impact on patients and families.

Hendrix believes that living the kitchen connoisseur may help prevent dementia. Actually, research conducted recently discovered that if people worked out, ate a healthy diet plan, stopped smoking and stored chronic health conditions for example diabetes away, 35 % of dementia cases all over the world might be avoided, he stated.

“It comes down to brain health on your entire existence,” stated Hendrix, who had been not associated with the research.

The report was printed online Sept. 5 within the journal JAMA Neurology.

For that study, Derby and her colleagues examined the speed of dementia in nearly 1,400 women and men who required part within the Einstein Aging Study on 1993 through 2015.

When participants joined the research, these were 70 or older and did not are afflicted by dementia.

During the period of the research, Derby’s team discovered that the speed of dementia dropped continuously.

One of the 369 people born before 1920, 73 developed dementia, time decreased to 43 one of the 285 born between 1920 and 1924.

Installments of dementia dropped to 31 for that 344 born between 1925 and 1929 and also to 3 for that 350 born after 1929.

“This isn’t unpredicted,” stated Dr. Mike Gandy, director from the Center for Cognitive Health at Mount Sinai Hospital in New You are able to City. “Similar trends happen to be documented in Europe.”

Gandy, who had been not associated with the research, believes much from the loss of the speed of dementia is caused by declining rates of stroke.

“As cardiovascular health has improved, stroke incidence has fallen,” he stated.

The healthiness of the bloodstream vessels within the brain lead towards the risk for dementia, Gandy stated.

“So you might predict that, with time, sustained decrease in stroke risk will be a precursor to reduced dementia risk,” he stated.

Even though the rate of dementia has dropped, the amount of cases will probably increase, Gandy stated.

“The maturing baby boom is really the overall quantity of dementia patients continuously rise whilst prevalence figures are falling slightly,” he stated.

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SOURCES: Carol Derby, Ph.D., research professor, Albert Einstein College of drugs, New You are able to City Mike Gandy, M.D., Ph.D., director, Center for Cognitive Health, Mount Sinai Hospital, New You are able to City James Hendrix, Ph.D., director, global science initiatives, Alzheimer’s Association Sept. 5, 2017, JAMA Neurology, online

Women in danger of Alzheimer&#039s Face Critical 10-Year Window, Study States

News Picture: Women at Risk for Alzheimer's Face Critical 10-Year Window, Study Says

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MONDAY, August. 28, 2017 (HealthDay News) — Women having a genetic predisposition for Alzheimer’s face a ten-year window whether they have much better likelihood of developing the condition than men concentrating on the same genetic risks, a brand new analysis suggests.

That window appears to happen between ages 65 and 75 — greater than ten years after the beginning of menopause, say College of Los Angeles researchers who reviewed 27 prior studies.

“Menopause and plummeting oestrogen levels, which typically begins at 51, may take into account the main difference,Inch stated study co-author Judy Pa. She’s a helper professor of neurology in the USC Neuroimaging and Informatics Institute.

“However, scientists still have no idea what’s responsible. Researchers have to study women 10, 15 or perhaps twenty years before their most vulnerable period to find out if you will find any detectable signals to point out elevated risk for Alzheimer’s in fifteen years,Inch Pa stated inside a college news release.

Based on the study, “genetically vulnerable” white-colored men and white-colored women aged 55 to 85 have similar odds for developing the condition except during individuals ten years, once the risk seems to leap for ladies.

But more research is required to prove the study’s assumptions, the research authors acknowledged.

The research challenges lengthy-held beliefs about Alzheimer’s risk. Additionally, it might have significant implications for ladies, since nearly two-thirds from the greater than 5 million Americans now coping with Alzheimer’s are female.

“Our discovery is essential since it highlights how numerous studies might be weighted toward women — a susceptible area of the population — to assist scientists more quickly identify effective drug interventions to slow or cure Alzheimer’s,” stated Arthur Toga, director from the Neuroimaging and Informatics Institute.

Case study centered on greater than 31,000 white-colored Americans and Europeans within the Global Alzheimer’s Association Interactive Network. All were identified as having Alzheimer’s between 55 and 85.

They honed in on the gene variant associated with Alzheimer’s, referred to as ApoE4.

They noted it’s generally assumed that ladies are in greater risk for Alzheimer’s simply because they have a tendency to live more than men. This really is likely an oversimplification.

They noticed that greater rates of cardiovascular disease and stroke among men would mean that men that survive into older age are healthier than their female peers and also at lower risk for Alzheimer’s.

The research authors recommended that at some point doctors trying to avoid the memory-robbing disease might treat women and men at different ages.

Not every women within their mid-60s or mid-70s are more inclined than men to build up Alzheimer’s, however. The ApoE4 gene is really a risk factor for that illness, but screening for this does not provide conclusive solutions by what the long run holds, they cautioned.

“There’s debate when it comes to whether people ought to know their ApoE status because it’s really a risk factor,” Pa stated. “It does not mean you are getting Alzheimer’s.”

They stated bigger and various studies which involve more ladies and minorities are necessary to confirm their findings.

The research was printed August. 28 in Journal from the Ama Neurology.

— Mary Elizabeth Dallas

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SOURCE: Keck Med school, College of Los Angeles, news release, August. 28, 2017

Do Less Nightly Dreams Mean Greater Dementia Risk in Seniors?

News Picture: Do Fewer Nightly Dreams Mean Higher Dementia Risk in Seniors?By Alan Mozes
HealthDay Reporter

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WEDNESDAY, August. 23, 2017 (HealthDay News) — Seniors who cut back time every night within the dream stage rest might be more prone to succumb to dementia as time passes, new information suggests.

Referred to as rapid eye movement (REM) sleep, this critical phase “happens in times at night time, and it is characterised by more dreaming and rapid eye movements,” described study author Matthew Pase. He’s a senior research fellow with Swinburne College of Technology around australia, along with a visiting investigator within the department of neurology at Boston College Med school.

“We discovered that persons experiencing less REM sleep during the period of an evening displayed an elevated chance of developing dementia later on,Inch Pase stated. He noted that for each 1 % stop by REM sleep, the seniors in the study saw their dementia and Alzheimer’s risk increase by about 9 %.

While prior studies have pointed for this REM-dementia link, the present analysis is the first one to link less REM sleep to some greater risk for developing dementia as much as 18 years lower the street. Which, stated Pase, implies that “alterations in REM sleep might not simply originate from dementia,” but instead potentially a adding cause.

Sleep moves through five distinct phases every night: light sleep a pre-deep sleep preparatory phase two subsequent stages of deep sleep and lastly REM sleep.

During REM — which repeats itself several occasions during the period of an average night — the eyes move rapidly. REM can also be characterised by greater brain activity, faster breathing and pulse, along with a relatively greater body’s temperature.

Pase’s study centered on 321 women and men aged 60 or more (average chronilogical age of 67) who’d took part in the Framingham Heart Study (FHS) between 1995 and 1998. The FHS is really a lengthy-term study which includes residents of Framingham, Mass.

The study team first tracked the sleep cycle from the women and men during the period of just one night. All of the patients were then tracked for indications of dementia for approximately 19 years (12 years, typically). Ultimately, 32 participants developed dementia. Twenty-four of individuals people developed Alzheimer’s.

The investigators figured that deep sleep patterns didn’t have effect on dementia risk. But REM patterns did.

Particularly, individuals to whom REM comprised 20 % of the total sleep didn’t will continue to develop dementia. However that number fell to 17 % of overall sleep among individuals who did develop dementia.

Which after modifying for additional factors — including cardiovascular disease risk, depression and medicine routines — they figured that individuals who spent a shorter period in REM and/or required longer to really enter the REM phase, faced a larger risk for dementia.

That stated, Pase stressed that “our results don’t test a reason-and-effect relationship,” but instead show a connection.

In regards to what might explain the hyperlink between REM and dementia, he noted that “more REM sleep might help safeguard connections within the brain, which become broken with dementia.”

However, “However,” he added, “lower REM sleep may end up using their company factors such as chronic stress or undiagnosed sleep problems, which might individually increase risk for dementia.”

The findings were printed online August. 23 within the journal Neurology.

Dr. Yvette Sheline, director from the Center for Neuromodulation in Depression and Stress in the College of Pennsylvania’s Med school in Philadelphia, pointed to prior animal research that indicated rodents which are deliberately disturbed while asleep have greater deposits of amyloid plaque within their brains. Such deposits are viewed to improve Alzheimer’s risk.

Meanwhile, Dr. Ricardo Osorio, an investigation assistant professor of psychiatry using the Center for Brain Health at NYU Langone Clinic in New You are able to City, noted that area of the complications with attempting to better understand REM’s affect on dementia risk “is the fact that we do not have a great explanation of why we’ve REM sleep.”

Based on Osorio, “We all know that [REM sleep] is essential for that survival on most mammalian and avian species” as well as seems to assist facilitate memory function and infant brain development. “But that’s about this,Inch he added.

Still, he stressed that many sleep-dementia studies have centered on the function of deep sleep instead of REM sleep.

“So, for me, this research revives REM sleep like a sleep stage that’s essential for thinking processes, which neural activity occurring particularly during REM may be crucial for normal memory consolidation and protective against Alzheimer’s,” Osorio stated.

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SOURCES: Matthew Pase, Ph.D., senior research fellow, Swinburne College of Technology, Australia, and visiting investigator, department of neurology, Boston College Med school Ricardo Osorio, M.D., research assistant professor, psychiatry, Center for Brain Health, NYU Langone Clinic, New You are able to City Yvette Sheline, M.D.. professor, psychiatry, radiology and neurology, and director, Center for Neuromodulation in Depression and Stress, College of Pennsylvania Perelman Med school, Philadelphia August. 23, 2017, Neurology, online

Popular Acid reflux Drugs Don&#039t Raise Chance of Alzheimer&#039s: Study

News Picture: Popular Heartburn Drugs Don't Raise Risk of Alzheimer's: Study

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FRIDAY, August. 18, 2017 (HealthDay News) — Broadly used acid reflux drugs known as proton pump inhibitors don’t seem to increase Alzheimer’s risk, according to a different study.

Prilosec, Nexium and Prevacid are generally used proton pump inhibitors.

Two previous studies reported a greater chance of dementia among individuals who required the drugs, that are generally utilized by seniors. Proton pump inhibitors work by reduction of producing stomach acidity.

However this new study discovered that utilisation of the drugs wasn’t connected by having an elevated chance of Alzheimer’s, even among individuals who required a greater dose or used the drugs in excess of 3 years.

The findings come from an analysis of information from Finland on nearly 71,000 Alzheimer’s patients and nearly 283,000 men and women without the condition.

The research shows individuals need not steer clear of the drugs because of fears about developing Alzheimer’s, stated the College of Eastern Finland researchers brought by Heidi Taipale, a postdoctoral investigator.

But lengthy-term use ought to be taken into consideration, because it’s been associated with decreased calcium and b12 absorption with serious intestinal infections, the research authors stated inside a college news release.

They stated several-third of older persons use proton pump inhibitors.

The research was printed lately within the American Journal of Gastroenterology.

— Robert Preidt

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SOURCE: College of Eastern Finland, news release, August. 7, 2017

Glen Campbell Dies at 81

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New bands legend Glen Campbell passed away at 81.

The singer and guitarist had endured from Alzheimer’s recently, NBC News reported.

“It’s using the heaviest of hearts that people announce the passing in our beloved husband, father, grandfather,” Campbell’s family stated inside a statement published on his website. No reason for dying was handed.

Campbell, the boy of the Arkansas sharecropper, had numerous hits, including “Rhinestone Cowboy,” “Gentle on my small Mind,” “Wichita Lineman,” and “Galveston.”

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Health Tip: Alzheimer&#039s Affects Sleep

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(HealthDay News) — Alzheimer’s affects many facets of living, including sleep.

The Nation’s Sleep Foundation states the condition may cause:

Caregivers should conserve a consistent sleep schedule. In the event that does not improve sleep, see a physician.

— Diana Kohnle

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Diet diary: Dates, the chocolate from trees

Compiled by Ishi Khosla Printed:This summer 29, 2017 1:44 am

Dates have a superior number of nutritional fibre (roughly 10 percent) with respect to the variety and amount of ripeness.

The date, or even the sweet fruit, dates back to 6000 BC. Dates were cultivated in prehistoric Egypt and then, Arabs spread them all over the world. They’re wealthy in carbohydrates, have less fats and proteins. At the top of nutritional fibre and minerals, dates really are a helpful energy source — ten pitted dates provide about 230 kcals. They create for helpful fuel specifically for athletes and individuals participating in heavy physical work. Usually, sugar in dates can depend on 70 percent.

Carbohydrates contained in dates are invert sugars (fructose and glucose), the type present in honey. This sugar works well for maintaining your fruit moist and prevents very formation. The soft dates are at the top of invert sugars however, dry dates have a superior content of sucrose (sugar).

Dates have a superior number of nutritional fibre (roughly 10 percent) with respect to the variety and amount of ripeness. Insoluble nutritional fibre may be the major fraction of nutritional fibre in dates also it helps relieve constipation and promotes good bowel function. Dates also contain small quantities of pectin (soluble fibre), that has cholesterol-lowering qualities.

Dates really are a wealthy supply of iron and contain other minerals for example potassium, selenium, copper, magnesium and calcium. They assist boost haemoglobin and therefore are helpful for anaemia. Dates also contain phosphorus, cobalt, boron, fluorine, manganese, sodium and zinc. They’re anti-cancer causing and helpful in avoiding cavities, owing partly for their fluorine content. Unlike other fruits, dates really are a modest supply of b vitamins and C, many of which get destroyed on drying.

Wealthy in anti-oxidants and phyto-nutrients (anthocyanins, carotenoids and phenolics), dates have impressive free-radical-scavenging and anti-cancer activity. Additionally, these help boost immune function and provide protection against coronary disease, liver disease, cancers, cataracts and macular degeneration, cognitive impairment and Alzheimers disease.

Some research has proven their anti-ulcer, anti-mutagenic, anti-diarrhoea, anti-inflammatory and anti-oxidant qualities too. However, more research is required to validate these claims.

Dates, being full of sugars, would be best taken as substitute of refined sugar or like a sweet option. While ordinary sugar is chemically refined and it has empty calories, dates really are a wealthy supply of valuable nutrients. Utilized in cereals, cakes, cookies and puddings, they add richness and may help boost the nutrient density of food. They create a great dessert, raw or stewed. Include them in your sugar allowance but control just how much you’ve particularly if you are watching unwanted weight or are diabetic.

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Targeting 9 Risks Could Prevent one in three Dementia Cases: Study

News Picture: Targeting 9 Risk Factors Could Prevent 1 in 3 Dementia Cases: Study

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THURSDAY, This summer 20, 2017 (HealthDay News) -Body-third of dementia cases worldwide may be avoided by having to pay focus on nine risks throughout existence, researchers say.

These measures include: remaining in class until you are a minimum of older than 15 reducing hearing problems, weight problems and bloodstream pressure in mid-existence (ages 45 to 65) and reducing smoking, depression, lack of exercise, social isolation and diabetes in later existence (65 and older).

Taking proper care of these risks might prevent 35 % of dementia cases, the research findings recommended. Compared, individuals major genetic risk factor -Known as ApoE — would prevent under one out of 10 dementia cases (7 %), the research authors stated.

The 3 risks that may potentially take advantage improvement in stopping dementia include: remaining in class (which may reduce dementia cases by 8 percent) reducing hearing problems in mid-existence (9 % less cases) and giving up smoking later in existence (five percent less dementia cases), the research reported.

The findings from 24 worldwide experts were released by The Lancet medical journal Thursday in the Alzheimer’s Association Worldwide Conference working in london, England.

About 47 million people worldwide have dementia. Time is anticipated to almost triple to 131 million by 2050, they stated.

“Acting now will vastly improve existence for those who have dementia as well as their families, and by doing this, will transform the way forward for society,” report lead author Gill Livingston, a professor at College College London, stated inside a journal news release.

Dementia is generally diagnosed later in existence. But brain changes associated with dementia generally begin to develop years before signs and symptoms become apparent, she noted.

“We feel that the broader method of protection against dementia which reflects these altering risks may benefit our aging societies which help to avoid the increasing quantity of dementia cases globally,” Livingston stated.

Study co-author Dr. Lon Schneider is really a professor in the College of Los Angeles Keck Med school. “Society must participate in methods to reduce dementia risk throughout existence, and enhance the treatment and care for individuals using the disease,” he stated.

“Including supplying effective and safe social and health-care interventions to be able to integrate individuals with dementia inside their communities. Hopefully this can also ensure that individuals with dementia, their own families and caregivers encounter a society that accepts and supports them,” Schneider stated.

— Robert Preidt

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SOURCE: The Lancet, news release, This summer 20, 2017

Special Training Plus Medication May Help Individuals With Advanced Alzheimer&#039s

News Picture: Special Training Plus Medication Might Help People With Advanced Alzheimer'sBy Amy Norton
HealthDay Reporter

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TUESDAY, This summer 18, 2017 (HealthDay News) — Individuals with advanced Alzheimer’s can relearn some fundamental skills once they receive special training together with medication, a little study suggests.

The study, which incorporated 20 Alzheimer’s patients, tested a course that mixes specialized “memory coaching” along with other services — including training and organizations to see relatives caregivers.

Researchers discovered that adding this program to medication — memantine (Namenda) — improved patients’ capability to perform everyday tasks, for example dressing and bathing themselves, over six several weeks.

As the study group was small, the outcomes demonstrate a fundamental point, based on lead investigator Dr. Craig Reisberg.

“Individuals with more-severe Alzheimer’s can continue to learn,” stated Reisberg, a professor of psychiatry at NYU Langone Clinic in New You are able to City.

As Alzheimer’s progresses, Reisberg described, individuals have growing complications with fundamental care, for example dressing, bathing and taking advantage of the bathroom .. Eventually, that worsens to begin incontinence and total reliance on caregivers.

The brand new study is dependant on the idea that patients could be “retrained” in individuals fundamental abilities — an idea which has become little attention due to the progressive nature of Alzheimer’s, based on Reisberg.

“It may sound amazing, that something as fundamental as teaching patients how you can toilet again, could be effective,” he stated. “But it’s.Inch

Reisberg presented study’s findings Sunday in the Alzheimer’s Association Worldwide Conference, working in london. Results presented at medical conferences are usually considered preliminary until they’re printed inside a peer-reviewed journal.

Greater than 5 million Americans live with Alzheimer’s, based on the Alzheimer’s Association. Many of their caregiving falls on family people.

Actually, the association states, Americans provided over 18 billion hrs of delinquent Alzheimer’s caregiving in 2016 alone.

There’s an enormous requirement for behavior therapies and support services to help ease that burden, based on geriatrics specialist Dr. Gisele Wolf-Klein.

The aim is not only to help patients, but to provide relief to exhausted caregivers, stated Wolf-Klein, who directs geriatric education for Northwell Health in Great Neck, N.Y.

We already have sources available, including organizations for caregivers, Wolf-Klein stated. There’s also “adult day centers” that provide Alzheimer’s patients an opportunity to be social, and could offer services which help with signs and symptoms.

“Individuals programs might help stabilize a few of the behavior signs and symptoms — for example ‘anti-social’ behavior — which are frequently probably the most disturbing area of the disease for families,” Wolf-Klein stated.

However the services at day centers or any other community centers vary around, based on the Alzheimer’s Association.

And couple of truly “cater” to patients within the more-advanced stages of Alzheimer’s, stated Barbara Vogel, a social worker with Northwell Health Geriatric Medicine and Palliative Care.

What’s key concerning the enter in the brand new study is the fact that it’s geared to the later stage from the disease, both Vogel and Wolf-Klein stated.

Based on Reisberg, this program is dependant on an idea his team calls “retrogenesis.” The concept is that individuals with Alzheimer’s lose their daily-care abilities within the reverse order that they developed them as youthful children.

They think that patients can, however, relearn individuals skills — if their training matches the developmental age where they acquired them to begin with.

They tested that concept by at random assigning 20 families either to undergo this program, or stick to standard care. Patients both in groups had to have memantine, and families within the standard-care group received referrals to community services — including day centers, organizations and physical and work-related therapy.

Caregivers within the program first were built with a general work out, Reisberg stated. Then therapists made home visits, to provide patients memory coaching within the skills they’d lost.

When patients were assessed after 28 days, individuals within the program scored greater on the standard way of measuring fundamental skills. In contrast to the study’s start, they’d improved by 6 points typically, versus 3 points within the standard-care group.

To place that inside a bigger context, Reisberg pointed to some 2003 trial that tested memantine alone (an effort he brought).

In contrast to the modest benefits seen there, patients within this study scored 7.5 occasions greater once they received the specialized training together with memantine.

“Taking medicine is important, but clearly we have to do more,” Reisberg stated. “The results of medicine are relatively small. The results of adding this [training] could be large.”

Bigger, longer-term scientific studies are needed, Wolf-Klein stated. And based on Reisberg, the outcomes of the one-year extension study is going to be not far off.

For the time being, Wolf-Klein recommended that families search for sources already obtainable in their community — by asking their physician, the neighborhood Alzheimer’s Association chapter, or nearby senior centers.

Medicare may cover some services for example work-related or physical rehabilitation. Even though day programs have no coverage, Vogel stated many offer “sliding scale” rates that will help families afford it.

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SOURCES: Craig Reisberg, M.D., professor, psychiatry, and director, Zachary and Elizabeth M. Fisher Alzheimer Disease Education and Sources program, NYU Langone Clinic, New You are able to City Gisele Wolf-Klein, M.D., director, geriatric education Northwell Health, Great Neck, N.Y. Barbara Vogel, L.M.S.W., social work coordinator, Northwell Health Geriatric Medicine and Palliative Care This summer 16, 2017 presentation, Alzheimer’s Association Worldwide Conference, London