Novel method prevents hearing problems in kids by 50%

By: IANS London Printed:September 13, 2017 6:31 pm

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This method is considerably more effective than the usual normal intra-tympanic injection and is accustomed to deliver any drug towards the ear. (Source: Thinkstock Images)

Scientific study has created a new magnetic delivery way in which prevents by 50 percent the hearing problems caused because of treatment with a broadly used chemotherapy drug.

Cisplatin is generally accustomed to treat childhood cancers but can result in permanent or severe high frequency hearing problems in nine from 10 children following treatment.

Steroids can help to eliminate cisplatin-caused hearing problems however they might also reduce the potency of cisplatin’s capability to kill cancer cells.

What this means is they should be directly sent to the cochlea to work and to avert this side-effect. Within the study, they used magnetic fields to push drug-covered iron nanoparticles in to the cochlea or even the body and reduced hearing problems in rodents given the chemotherapy drug cisplatin by 50 percent.

“It is excellent news that progress has been made towards finding new methods to safeguard children’s hearing following cancer treatment with cisplatin which in turn causes the physical hair cells within the cochlea that identify seem to die and may leave cancer survivors who’ve already been through a traumatic experience depressed and isolated,” stated Rob Holme, Director of Research at Action on Hearing Problems — a United kingdom-based charitable organization.

The approach, printed in Frontiers in Cellular Neuroscience, is considerably more effective than the usual normal intra-tympanic injection and is accustomed to deliver any drug towards the ear and may also be used to provide drugs into eyes or in to the skin, they noted.

Researchers anticipate the novel approach doubles to provide an array of drug, gene and stem cell-based treatments to ultimately treat various sorts of hearing problems.

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